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压力太大会丧失记忆力!还能使大脑萎缩?

(2018-10-29 11:42)
标签:压力的危害 

Listen up, gen-Xers and millennials, and, well, everybody who has a brain. If you live a high-stress life, you could have memory loss and brain shrinkage before you turn 50, according to a study published Wednesday in the journal Neurology.

听着,x一代和千禧一代,每个人都拥有一个大脑。本周三发表在《神经学》杂志上的一项研究表明,如果你的生活压力很大,那么在你50岁之前,你的记忆力就会丧失,大脑也会萎缩。

Higher levels of cortisol, a stress hormone, seem to predict brain function, brain size and performance on cognitive tests, said study author Dr. Sudha Seshadri, professor of neurology at UT Health San Antonio.

研究报告的撰写者、圣安东尼奥德克萨斯大学健康学院的神经学教授萨哈.a塞沙德里博士表示:“皮质醇是一种应激激素,它的水平越高,似乎就越能预测大脑的功能、大脑的大小和认知测试的表现”。

We found memory loss and brain shrinkage in relatively young people long before any symptoms could be seen, Seshadri said. "It’s never too early to be mindful of reducing stress."

塞沙德说:“我们发现相对而言较年轻的人在未出现任何症状之前就已经出现了记忆力减退和大脑萎缩。”“注意减轻压力永远不会太早。”

High stress connected to memory loss

与记忆丧失有关的高压力

Previous studies have found a relationship between cortisol and dementia risk, but the focus has been mostly on the elderly and the memory area of the brain, called the hippocampus.

之前有研究已经发现皮质醇和痴呆症风险之间的关系,但研究重点主要集中在老年人群体和大脑的记忆区域——海马体。

Among the new study’s strengths, said Seshadri, is that it looked at a group of men and women with an average age of 48 and did MRI brain scans of the entire brain, not just the hippocampus.

塞沙德指出,这项新研究的优势之一是,它观察了一组平均年龄为48岁的男性和女性,并对他们的整个大脑进行了核磁共振扫描,而不仅仅是海马体。

Researchers chose more than 2,000 people with no signs of dementia and gave them various psychological exams to measure their thinking skills.

研究人员选择了2000多名没有患有痴呆症症状的人,并对他们进行了各种心理测试,以测试他们的思维能力。

About eight years after initial testing, the group was reevaluated. Blood serum cortisol was measured before breakfast. Then brain MRIs were done and the series of memory and cognitive tests repeated.

在最初的测试大约8年后,该小组被重新评估。他们在早餐前空腹测量血清皮质醇。然后他们进行脑核磁共振成像,并重复一系列记忆和认知测试。

After adjusting the data to consider age, sex, body mass and smoking, the study found people with the highest levels of cortisol had the most memory loss.

在调整数据以考虑年龄、性别、体重和吸烟状况后,研究发现皮质醇水平最高的人记忆力损失最大。

Stress affects brain structure, too

压力也会影响大脑结构

What was surprising, said Foley, was the study’s findings of the effects of cortisol on brain structure.

弗利称,令人惊讶的是,这项研究发现皮质醇对大脑结构的影响。

High levels of cortisol were associated with more damage to the parts of the brain that move information throughout the brain (corona radiata) and between the two hemispheres of the brain (corpus callosum).

高水平的皮质醇会对大脑中传递信息的区域(放射冠)和大脑两个半球(胼胝体)造成更大的伤害。

In addition, the brains of people with higher cortisol levels had smaller cerebrums, the two hemispheres of the brain responsible for thought, emotions, speech and muscle functions, the study found.

此外,研究还发现,皮质醇水平较高的人的大脑(大脑中负责思考、情感、语言和肌肉功能的两个半球)也更小。

            

 

 


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